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Flora Immune Lactobacillus Sporogenes Probiotic by Scott Siegel

Is There a Connection between Microbes, Health, and Longevity?

To fully appreciate the benefits of a product such as Flora Immune, it is helpful to examine the historical understanding of the role of microbes in the overall health of the body. Through out history, using fermented foods have been used as dietary staples for many cultures--from the sauerkraut of the Germans to the kefir of the Finnish. These foods have been noted to be "longevity foods". So what was it in these foods that contributed to long life? From the days of Louis Pasteur and the "germ theory" to the continuing work of Dr. Élie Metchnikoff, clarity on why microbes are essential to life unfolds.1


In 1905, Dr. Metchnikoff advocated his Theory of Longevity. He proclaimed that to grow into old age and be disease free and healthy (full of vitality), the continuous use of Lactobacilli was necessary. He was the first doctor to recognize the problems caused by the "die off" of friendly bacteria in the intestines and the first doctor of modern medicine to recognize the disorder Dysbiosis (irregular and abnormal intestinal flora). With this disorder, pathogenic bacteria, fungi, virus and parasites hang around longer, which allows them to proliferate and run rampant inside the body.2

The Golden Ages

But such understandings and discoveries eventually lost favor in light of new medical practices. With the ending of World War II, the modern age of medicine began, the so-called Golden Age of Medicine. Standard medical practices were established which prevail to this day. If there is a problem in the human body--cut it out, or kill it with antibiotics. New drugs were created by the pharmaceutical industry to support these practices. The power of an individual's health shifted from the family doctor to the large pharmaceutical corporations.
3



Now after 50 years of experience with the Golden Age of Medicine we have lengthened our lives, but have ushered in, "The Age of Chronic Diseases". The medical establishment is beginning to admit it does not have the means to treat many chronic diseases and many individuals as well as physicians recognize that Dysbiosis is currently involved with the contributing factors of chronic diseases. Dys-means faulty and -bios means life and growth. This implies faulty life. In biological terms the phrase intestinal Dysbiosis is used for an imbalanced bacterial flora in the intestines. The microflora is dysbiotic. Normally it is understood that this condition includes harmful metabolic activity of the flora.4


Could our forefathers have known that is was the microbes in their foods that caused lactic acid formation and contributed to longevity and health? Regardless of what they understood, we can now combine the wisdom of the ancients and the knowledge of modern science to create a probiotic (meaning pro-life) environment in our intestines.



The Necessity of Probiotics

Our diet, lifestyle, and environment have changed significantly from that of our grandparents. Maintaining a balance of friendly verses unfriendly bacteria in our gastrointestinal tract is more of a challenge today than in the past. The problem arises when the numbers of friendly bacteria become compromised through out life due to the use of antibiotics and sulfa drugs, diet, stress and age
.5,6

Lactic acid bacteria or lactobacilli are the most useful microbes for humans and are part of the normal commensal flora of the mouth, small intestine, and large intestine. 7,8 They are present in large number in feces, and within the first 2 to 3 days after birth the alimentary canal is colonized with lactobacilli.9,10,11

To keep these friendly bacteria thriving, supplementation is absolutely necessary today. A properly functioning intestinal tract is one of the body's first lines of defense against invaders. The immune system of the gut is one's insurance to great health.


How Effective is Lactobacillus Acidophilus?

There are over 200 different strains of Lactobacillus. However, the most commonly "used" probiotic is Lactobacillus acidophilus. But Lactobacillus acidophilus loses most or all of its potency before the body is able to use it. The cells of Lactobacillus acidophilus do not survive in bacterial gastric juice due to its nonspore-forming nature. Very few cells are able to reach the intestines and are unable to produce sufficient lactic acid to inhibit the growth of pathogens. Further more, acidophilis-bifidus produces D (-) lactic acid, which is slowly and incompletely metabolized in excess and causes metabolic acidosis and can be toxic to the brain.12,13

Yet, Lactobacillus acidophilus is the common bacteria found in our sour milk products and promoted by health care professionals. Thus it stands to reason that even with acidophilus supplementation, chronic and acute illnesses are on the rise.
14


Where Are the Friendly Microbes?

So where can we find the necessary microbes that were present in the non-processed foods of the past? This is a very important question to answer. Even if we did eat fermented foods full of healthy microbes the problem lies with current processing practices. All foods are pasteurized and that KILLS everything. Yogurt is a perfect example. In order to ensure that other pathogenic microbes do not culture, yogurt is pasteurized, which kills all enzymes. Then animal strains of microbes are added.


Good News for a Modern Day Problem

In 1949, Lactobacillus sporogenes was first isolated in green malt by Professor Nakayama at Yamanashi University in Japan. This plant material has a non-protein shell that protects the bacteria which remains dormant inside the shell. In fact, this bacterium is also known as Bacillus coagulans, is an aerobic, is spore-forming, and does not have any animal by products or known toxicity. It is a harmless transient bacterium naturally occurring in the intestine and plays a major housekeeping role. Its responsibilities are to:


* produce substantial amounts of B complex vitamins
* synthesize vitamin K
* assist nutrient absorption into the body
* produce oxygen in the small intestine
* produce an abundant supply of lactic acid for digestion
* consume old putritive fecal matter
* clean "friendly bacteria" and destroy "bad bacteria"
* produce L(+) Lactic acid, which is completely and efficiently metabolized to glycogen
* protect friendly resident bacteria in the presence of antibiotics
* support digestive enzymes required for the digestion of various carbohydrates, fats, and proteins
18,19




Why is Lactobacillus Sporogenes Effective?

Unlike its close cousin, Lactobacillus acidophilus and many other strains, Lactobacillus sporogenes is a spore-bearing, positive rod, and an aerobic bacterium. The spores are extremely stable and have a long shelf life. Survivability of the bacterium is the key to maintaining intestinal health. Most probiotics on the market today can not survive the pH changes that take place in the intestines.20,21,22

Even more alarming is the die-off rate from the time they are manufactured to the time of consumer use. The following supports the survivability of L. sporogenes:
23


1. Lactobacillus Sporogenes shell is non-protein and the bacteria are made up of proteins.

A. Survives with or without oxygen
B. Survives at room temperature; no refrigeration is necessary
C. Survives light
D. Survives hydrochloric and bile acids

2. Sporogenes comes out of its shell when it reaches the small intestines and
E. Survives any pH
F. Proliferates in great numbers
G. Decreases the number of candida



The spores of Lactobacillus sporogenes travel well through the human gut just like a paratrooper jumping out of an airplane. The spore coat absorbs moisture and begins to swell in the stomach. Once in the small intestines, the friendly paratrooper releases itself from the spore. Immediately this bacterium is ready to germinate and multiply. Lactobacillus sporogenes doubles every 30 minutes. Upon reaching the lower bowel, a mildly acidic environment is created. The L (+) lactic acid environment allows friendly bacteria to survive and prevents overgrowth of pathogens.24 The length of this trooper's mission is three days. At that time the bowel releases these transient bacteria.



Lactobacillus Sporogenes Fulfills World Health Organization Recommendations

Although standards for Lactobacillus acidophilus were established in the USA, it was reported that preparations contain less than 1000 cells of viable bacteria.25,26 The enthusiasm over the therapeutic properties of Lactobacillus has been great among scientists and physicians; however there is little evidence that such Lactobacillus acidophilus preparations are effective.27,28
Thus, there is uncertainty about survival of Lactobacillus acidophilus in carrier products of pharmaceutical preparations and production of D (-) lactic acid during fermentation which may cause acidosis, especially with infants.29,30 Furthermore the World Health Organization has recommended restricted intake of D (-) lactic acid, and in the infant Nutritional Program such products should be avoided.31 L. sporogenes on the other hand produces L (+) lactic acid.32,33 This bacterium is used extensively in Japan and is approved by the Japanese Ministry of Health, an organization equivalent to our FDA.34

Within the past 10 years L. sporogenes has been introduced to the United States and is gaining favor with physicians as a replacement for the less effective popular probiotics on the market. Research studies in hospitals showed an improvement rate in intestinal complaints such as gas and bloating, constipation, diarrhea and indigestion (usually in 4 to 5 days) from patients using L. sporogenes.35Several studies were of patients who had surgery; others studied patients who had chemotherapy.36 Studies have also showed that diarrhea in newborns was also treated successfully.37






Why Flora Immune?

Lactobacillus Sporogenes is the primary ingredient in Flora Immune. It is a very strong and hardy, robust intestinal flora designed for the dietary and environmental challenges we face today. This bacterium will enable the bowel to move more frequently by balancing the ratio of putrefactive bacteria to "friendly" bacteria. Unlike most probiotic products on the market, L. Sporogenes not only survives the harsh pH condition of the digestive tract but further creates and maintains the proper pH environments. What is truly amazing about this armored bacterium is the ability it has to withstand the hydrochloric acid of the stomach and bile acids in the intestines. This is and considered by many to be a "miracle in a bottle." Because of this feature, L. Sporogenes proliferates in great numbers and decreases the number of candida which is a major upset for gut health. In addition, the production of oxygen, B complex and lactic acid (L+), become more readily available to the body therefore nutrient absorption is enhanced. A natural reward of this process is ENERGY and a feeling of WELL BEING.

Flora Immune is convenient to use due the fact these microbes are spores and NO refrigeration is necessary. There is no need to worry about light sensitivity or temperature changes.Flora Immune supports implantation of new strains of friendly, resident bacteria. If using a probiotic now, Flora Immune will enhance the effect of all other cultures.





Death Begins in the Colon.

How safe would your home be in the middle of a busy city without the service of a police force? If an uninvited guest happens to show up, a policeman is a welcome site. He is there for surveillance and protection. The lower bowel houses a population of roughly 100 trillion bacteria which needs the same action.


There is an old saying that "DEATH BEGINS IN THE COLON." When the intestines have a surplus of bacteria and toxins, many digestive discomforts occur. Symptoms include:


* Constipation
* Hemorrhoids
* Diverticular Disease
* Flatulence
* Cohn's Disease
* Ulcerative Colitis
* Irritable Bowel Syndrome

When the bowel becomes so toxic of the gases and undigested matter, pressure is generated. This environment becomes a breeding ground for many pathogenic invaders to flourish. Parasites, fungus, virus, and bacteria are now the police force of the gut and anarchy is established. Instead of the intestinal membrane bursting (many cases it does), these toxic substances pierce holes in the intestinal membrane and penetrate the blood stream. Auto intoxication contributes too many autoimmune disorders. These include:

* Diabetes
* Acne
* Chronic Fatigue
* Lupus
* Gall stones
* Fibromyalgia
* Allergies
* Gout
* Rheumatoid Arthritis
* Varicose Veins
* Obesity
* Hypertension
* Psoriasis


Picture your digestive tract like a beautiful, grassy carpet of golf greens in the spring time. Summer comes and the harsh weather stresses the grass. Many brown barren patches appear, therefore; the lawn keeper removes the old grass, reseeds and waters. The same happens to your gut. This is why it is important to constantly cleanse, replant, and nourish the gastro intestinal tract.

When there is a healthy microbial balance in the gut, this multicultural community lives in harmony. This is called "eubiosis". However; the standard American diet (SAD) and lifestyle prevents eubiosis and ushers in Dysbiosis (unfriendly gut environment).




How does Flora Immune and Aloe Immune Work Together?

To complete the effectiveness of Flora Immune, a food for this transient trooper is necessary. Fructooligosaccarides (FOS). FOS promotes the resurgence of good bacteria by "feeding" them the needed fuel.

When Flora and Aloe Immune are combined, this synergistic duo creates a very effective surveillance team. L. sporogenes maintains housekeeping while the aloe polymannans signal for defense and ultimately repair damaged tissue. Immunological factors may be restored and better nutrition is delivered to all tissues of the gut and cells of the body. The combination of these two products will enable the immune system to become more functional.

Remember, you are what you eat and what you don't digest! Detoxification and elimination is your first line of defense towards immunity. Optimal health begins and ends with a well balanced gastrointestinal tract that calibrates the Immune system. How effective is your digestive system?


References

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1 Food Technology 43, 92, 1989

2 Élie Metchnikoff, the Prolongation of Life. Heiemann. New York. 1907. One of the first books of this century in which the prospect of the Optimum Lifespan was treated seriously.) Metchnikoff, E. (1910), "The Prolongation of Life", William Heinemann, London.

3 Lenore Skomal, Health News July 26, 2000

4 Functional Medicine by Dr. Helmut W., Schimmel, M.D., D.M.D. with Victor Penzer, M.D., D.M.D., D.Sc.

5 Goodwin, C.S. (Ed) (1984), "Microbes and Infections of the Gut" p. 5, Blackwell Scientific Publications, London

6 Keogh, B.P. (1978), Aust. J. Dairy Tech., June, 41.

7 Hawkworth, G. et al (1971), J. of Microbiol., 4, 451.

8 Smith, H.W., and Crabb, W.E. (1961), J. Path. Bact., 82, 53.

9 Hall, I.C., and O'Toole, E. (1935), Am. J. Dis. Child., 49, 390

10 Sayder, M.L. (1940), J. Inf. D., 66, 1.

11 Stewart, F.S. and Beswick, T.S.L. (eds) (1977), Bacteriology, Virology and Immunity for Students of Medicine, 10th Edition.

12 British Medical Association and the Pharmaceutical Society of Great Britain - British National Formulary (1984) p. 54.

13 Martindale - The Extra Pharmacopsia (1982), 28th Ed. P. 786, the Pharmaceutical Press, London

14 Robinson, R.E. (Ed), (1986), Development in Food Microbiology, p. 153, Elsevier Applied Science Publishers, U.K

15 Gilliland, S.E. (1979), J. Fd. Prot., 40, 760.

16 Gilliland, S.E., and Speck, M.L. (1977), J. Fd. Prod., 40, 760.

17 Robinson, R.E. (Ed), (1986), Development in Food Microbiology, p. 153, Elsevier Applied Science Publishers, U.K

18 Speck, M.L. (1976), J. Dairy Sci., 59, 338.

19 Speck, M.L. (1978), J. Fd. Prot., 41, 135.

20 Claus, D. (1980), DSM, Grisebachstrasee 8 D-3400, Gottingen, Germany

21 Nakayama, O., and Sakaguchi, K. (1950), J. Agr. Chem. Soc., Japan, 23, 513-517.

22 Nakayama, O. and Ueno, S. (1952), J. Agr. Chem. Soc., H Japan, 26, 117-120.

23 Nakayama, O. (1960), Studies on the Spore-bearing Lactic acid Bacteria. The Bulletin of the Faculty of Agriculture Tamagawa University, No. 1, 73.

24 Gilliland, S.E. (1979), J. Fd. Prot., 40, 760.

25 Bass (1923), J. South Med. Assoc., 16, 1.

26 Lockic, B. (1980), Dairy Products, 8, 3.

27 British Medical Association and the Pharmaceutical Society of Great Britain - British National Formulary (1984) p. 54.

28 Martindale - The Extra Pharmacopsia (1982), 28th Ed. P. 786, the Pharmaceutical Press, London.

29 Oh, M.S. et al (1979), New England J. Med., 301, 249.

30 Zallubriga, A. et al (1970), Halvet Poediatr. Acta, 25, 1.

31 Alm, L.(1982), J. Dalry Sel., 65, 515.

32 Claus, D. (1980), DSM, Grisebachstrasee 8 D-3400, Gottingen, Germany

33 Nakayama, O. (1960), Studies on the Spore-bearing lactic acid Bacteria. The Bulletin of the Faculty of Agriculture Tamagawa University, No. 1, 73.

34 Japanese Government Ministry of Health, and Welfare Certificate Oct.26, 1972. Sporlac and Lacbon are Japanese registered trademarked names for Lactobacillus Sporogenes.

35 Literature No. 1 on Lacbon, (1965). Mashita, H. et al.: J. New Remedies & Clinics 13, 977 (1964). Yamada, H. et al.: Chiryoyaku-ho 638, 14 (1964).

36 "Dr. Y. Hara using Lacbon (L. Sporogenes) along with Antibiotics and Chemotherapeutic agents found excellent results. He emphasized the advantage of adding Lacbon (L. sporogenes) to antibiotics."

37 Dr. Rk Dhangade & Dr. R. Anyaneyulu MMJ Vol. XXX, No. II, Page 473 & 474, 1977

Benefits of Flora Immune TM


* Increases energy
* Stops yeast infection
* Controls Candida
* Can be taken with Antibiotics
* Enhances the immune system
* Brushing with Flora Immune helps control gum disease
* Controls diarrhea
* Relieves constipation
* Reduces harmful cholesterol (LDL)
* Increases beneficial cholesterol (HDL)
* Produces the B-group vitamins
* Produces enzyme to break down proteins
* Produces enzyme to break down complex fats
* Produces L+ Lactic acid unlike acidophilus production of D- Lactic acid
* Greatly reduces and eliminates harmful bacterial
* Increases beneficial bacteria and restores balance of the intestinal flora
LACTOBACILLUS SPOROGENES is much superior to LACTOBACILLUS ACIDOPHILUS due to its excellent preservability, high proliferating ability in the intestinal tract, excellent intestinal conditioning, and restoration of disturbed ecological balance in the gut. (Federal Register, March 21, 1975. The New England Journal of Medicine, Vol.31, No.5, Pgs.249-252 (1979)


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